Inhibition of skeletal muscle development: less differentiation gives more muscle.

@article{Fchtbauer2002InhibitionOS,
  title={Inhibition of skeletal muscle development: less differentiation gives more muscle.},
  author={Ernst-Martin F{\"u}chtbauer},
  journal={Results and problems in cell differentiation},
  year={2002},
  volume={38},
  pages={143-61}
}
The fact that stem cells have to be protected from premature differentiation is true for many organs in the developing embryo and the adult organism. However, there are several arguments that this is particularly important for (skeletal) muscle. There are some evolutionary arguments that muscle is a "default" pathway for mesodermal cells, which has to be actively prevented in order to allow cells to differentiate into other tissues. Myogenic cells originate from very small areas of the embryo… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.

Similar Papers

Loading similar papers…