Inhibition of sialidases from viral, bacterial and mammalian sources by analogues of 2-deoxy-2,3-didehydro-N-acetylneuraminic acid modified at the C-4 position

@article{Holzer1993InhibitionOS,
  title={Inhibition of sialidases from viral, bacterial and mammalian sources by analogues of 2-deoxy-2,3-didehydro-N-acetylneuraminic acid modified at the C-4 position},
  author={Cindy T. Holzer and Mark von Itzstein and Betty Jin and Michael S. Pegg and Wendy P. Stewart and Wen-Yang Wu},
  journal={Glycoconjugate Journal},
  year={1993},
  volume={10},
  pages={40-44}
}
The inhibition of sialidase activity from influenza viruses A and B, parainfluenza 2 virus,Vibrio cholerae, Arthrobacter ureafaciens, Clostridium perfringens, and sheep liver by a range of 2-deoxy-2,3-didehydro-N-acetylneuraminic acid analogues modified at the C-4 position has been studied. All substitutions tested resulted in a decrease in the degree of inhibition of the bacterial and mammalian sialidases. For sialidases from influenza viruses A and B, on the other hand, most of the… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.

Explore Further: Topics Discussed in This Paper

Citations

Publications citing this paper.
SHOWING 1-10 OF 23 CITATIONS

References

Publications referenced by this paper.
SHOWING 1-2 OF 2 REFERENCES

International Patent App . WO 9116320 - A 91 . 10

  • M yonItzstein, Wu W-Y, B Danylec, B Jin
  • 1991

International Patent App. WO9116320-A91.10.31 (9147) CA 117:49151y

  • M von Itzstein, W-Y Wu, +19 authors CR Penn
  • Bioehem Int
  • 1991

Similar Papers

Loading similar papers…