Inhibition of several strains of influenza virus in vitro and reduction of symptoms by an elderberry extract (Sambucus nigra L.) during an outbreak of influenza B Panama.

@article{ZakayRones1995InhibitionOS,
  title={Inhibition of several strains of influenza virus in vitro and reduction of symptoms by an elderberry extract (Sambucus nigra L.) during an outbreak of influenza B Panama.},
  author={Zichria Zakay‐Rones and Noemi Varsano and Michał Złotnik and Orit Manor and Lior Regev and Miriam Schlesinger and Michael Mumcuoglu},
  journal={Journal of alternative and complementary medicine},
  year={1995},
  volume={1 4},
  pages={
          361-9
        }
}
A standardized elderberry extract, Sambucol (SAM), reduced hemagglutination and inhibited replication of human influenza viruses type A/Shangdong 9/93 (H3N2), A/Beijing 32/92 (H3N2), A/Texas 36/91 (H1N1), A/Singapore 6/86 (H1N1), type B/Panama 45/90, B/Yamagata 16/88, B/Ann Arbor 1/86, and of animal strains from Northern European swine and turkeys, A/Sw/Ger 2/81, A/Tur/Ger 3/91, and A/Sw/Ger 8533/91 in Madin-Darby canine kidney cells. [...] Key Method A placebo-controlled, double blind study was carried out on…Expand
Inhibitory activity of a standardized elderberry liquid extract against clinically-relevant human respiratory bacterial pathogens and influenza A and B viruses
TLDR
It was shown that a standardized elderberry liquid extract possesses antimicrobial activity against both Gram-positive bacteria ofStreptococcus pyogenes and group C and G Streptococci, and the Gram-negative bacterium Branhamella catarrhalis in liquid cultures, and an inhibitory effect on the propagation of human pathogenic influenza viruses. Expand
Anti-influenza virus activity of two extracts of the blackcurrant (Ribes nigrum L.) from New Zealand and Poland.
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The extract of Blackcurrant could disinfect all of 4 IFV strains the authors examined and showed definite potential for use as a disinfectant and antiseptic agent to prevent IFV infection. Expand
Anti-Influenza Virus Effects of Elderberry Juice and Its Fractions
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CJ-E had a beneficial effect by the stimulating immune response and preventing viral infection, and high-molecular-weight fraction HM, which contained acidic polysaccharides, showed relatively strong defense against IFV infection. Expand
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A potent anti-influenza virus activity was discovered in summer leaves of Japanese wasabi, and ethanol extracts inhibited influenza virus replication regardless of the hemagglutinin antigen type. Expand
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The blackcurrant extract still showed antiviral and antibacterial activities after the pH had been made neutral with sodium hydroxide, suggesting that these activities are not the result of acidic reactions or of components precipitated at a neutral pH. Expand
SWINE FLU AND ITS POSSIBLE THERAPY
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The most frequently reported symptoms in this disease are fever, cough, and sore throat; 25% of patients report diarrhoea, and a further 25% report vomiting, and myalgia and joint pains may also be present. Expand
The effect of Sambucol, a black elderberry-based, natural product, on the production of human cytokines: I. Inflammatory cytokines.
TLDR
It is concluded that, in addition to its antiviral properties, Sambucol Elderberry Extract and its formulations activate the healthy immune system by increasing inflammatory cytokine production and might therefore be beneficial to the immune system activation and in the inflammatory process in healthy individuals or in patients with various diseases. Expand
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Proven anti‐influenza virus effects of the extracts were shown, and virus titres in culture fluids of the cells treated with 100 μg/mL of Kurokarin extract were completely suppressed, indicating that the extract inhibited the virus release from the infected cells. Expand
Anti-influenza activity of elderberry (Sambucus nigra)
Abstract Elderberry extract is effective in treatment of flu. This study aimed to determine the mechanism of action of elderberry and its primary active compound, cyanidin 3-glucoside (cyn 3-glu),Expand
Antiviral activity of Sambucus FormosanaNakai ethanol extract and related phenolic acid constituents against human coronavirus NL63
  • J. Weng, Chen-Sheng Lin, +6 authors Cheng-Wen Lin
  • Biology
  • Virus Research
  • 2019
TLDR
Investigating the antiviral activity of Sambucus Formosana Nakai stem ethanol extract and some phenolic acid constituents revealed that caffeic acid could be the vital component with anti-HCoV-NL63 activity, and the finding could be helpful for developing antivirals against HCoVs. Expand
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