Inhibition of ribulose-1,5-bisphosphate carboxylase/oxygenase by xylulose 1,5-bisphosphate.

@article{McCurry1977InhibitionOR,
  title={Inhibition of ribulose-1,5-bisphosphate carboxylase/oxygenase by xylulose 1,5-bisphosphate.},
  author={S D McCurry and N. E. Tolbert},
  journal={The Journal of biological chemistry},
  year={1977},
  volume={252 23},
  pages={8344-6}
}
Xylulose 1,5-bisphosphate is a potent inhibitor of ribulose-1,5-bisphosphate carboxylase/oxygenase. The enzyme was inhibited 50% at a xylulose 1,5-bisphosphate concentration of 0.56 micrometer and an enzyme concentration of 0.14 micrometer. When both ribulose 1,5-bisphosphate and xylulose 1,5-bisphosphate were added simultaneously to the enzyme, this inhibition appeared to be competitive. A preincubation of 20 to 30 min was needed for maximum inhibition. The inhibitory effect of this compound… CONTINUE READING

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