Inhibition of resistance to hemopoietic allo-grafts in granulocyte colony-stimulating factor transgenic mice.

@article{Kokai1996InhibitionOR,
  title={Inhibition of resistance to hemopoietic allo-grafts in granulocyte colony-stimulating factor transgenic mice.},
  author={Yasuo Kokai and Hiroto Kaneko and K Izuka and Akihiro Matsuura and Junichiro Fujimoto},
  journal={European journal of immunology},
  year={1996},
  volume={26 1},
  pages={115-9}
}
Transplanted allogeneic marrow cells often fail to engraft in a lethally irradiated host. This phenomenon, termed resistance to allogeneic marrow grafts or alloresistance, is well documented, although its mechanism is not yet understood. Transplantation of major histocompatibility complex disparate allogeneic marrow cells into mice transgenic for granulocyte colony-stimulating factor (G-CSF) showed donor-derived spleen colonies (CFU-S) and resulted in stable allogeneic chimerism with excellent… CONTINUE READING