Inhibition of replication forks exiting the terminus region of the Escherichia coli chromosome occurs at two loci separated by 5 min.

@article{Massy1987InhibitionOR,
  title={Inhibition of replication forks exiting the terminus region of the Escherichia coli chromosome occurs at two loci separated by 5 min.},
  author={Bernard de Massy and Samir Bejar and Jean Michel Louarn and J. P. Bouch{\'e}},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1987},
  volume={84 7},
  pages={1759-63}
}
The replication cycle of Escherichia coli strains duplicating their chromosome from the same plasmid origin placed at various locations or of strains having undergone a major inversion event along the origin-to-terminus axis was studied by marker-frequency analysis. It was observed that replication forks are unidirectionally inhibited at two loci of the termination region: counterclockwise-moving forks are inhibited at terminator T1 (28.5 min), and forks moving in the opposite direction are… CONTINUE READING

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