Inhibition of release of prostaglandins and leukotrienes from zymosan-stimulated mouse peritoneal macrophages by anisodamine

@inproceedings{Jian1989InhibitionOR,
  title={Inhibition of release of prostaglandins and leukotrienes from zymosan-stimulated mouse peritoneal macrophages by anisodamine},
  author={Li Jun-ying Yu Jian},
  year={1989}
}
[3H]arachidonic acid (AA)prelabeled mouse peritoneal macrophageswere stimulated by zymosan to release [3H]AA metabolites.The major labeled products which were co-chromatographed with the authentic PG and LT standareds by TLC and determined by liquid scintillation were LTC4,LTB4,TXB2,6-keto-PGF1α and PGE2 Aniso-daminc (Ani)significantly inhibited the zymosan-induced release of PG and LT from mouse,macrophages in a dose-dependent manner.Both the total 3H and each of AA metabolites released in… CONTINUE READING