Inhibition of rat GSH S-transferases by ethylene dibromide.

Abstract

Incubation of ethylene dibromide (EDB) (37 mM) with a mixture of rat hepatic cytosol GSH S-transferases at 25 degrees resulted in diminished activity towards 1-chloro-2,4-dinitrobenzene (CDNB) and 3,4-dichloronitrobenzene (DCNB). The loss of both activities followed pseudo first order kinetics with a rate constant of 0.13 +/- 0.03 min-1. The concentration… (More)

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@article{Ivanetich1984InhibitionOR, title={Inhibition of rat GSH S-transferases by ethylene dibromide.}, author={Kathryn M Ivanetich and Michael Ziman and R E Mennie and Karin Ann Eidne and Anne V. Corrigall and R E Kirsch}, journal={Research communications in chemical pathology and pharmacology}, year={1984}, volume={45 2}, pages={233-42} }