Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs.

@article{Vane1971InhibitionOP,
  title={Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs.},
  author={J. Vane},
  journal={Nature: New biology},
  year={1971},
  volume={231 25},
  pages={
          232-5
        }
}
  • J. Vane
  • Published 1971
  • Chemistry, Medicine
  • Nature: New biology
  • Experiments with guinea-pig lung suggest that some of the therapeutic effects of sodium salicylate and aspirin-like drugs are due to inhibition of the synthesis of prostaglandins. 
    7,899 Citations

    Paper Mentions

    INTERVENTIONAL CLINICAL TRIAL
    The purpose of the study is to test higher versus lower doses of aspirin on markers of atherosclerosis in patients who have had a heart attack.  
    ConditionsAtherosclerosis, Cardiovascular Diseases, Myocardial Infarction
    InterventionDrug
    The mode of action of aspirin and similar compounds.
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    • 1976
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    Prostaglandins and aspirin: An alternative view
    • M. Smith
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    • Agents and Actions
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    Effect of indomethacin in asthma: evidence against a role for prostaglandins in its pathogenesis.
    • A. Smith
    • Medicine
    • British journal of clinical pharmacology
    • 1975
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