Inhibition of pro-inflammatory markers in primary bone marrow-derived mouse macrophages by naturally occurring flavonoids: analysis of the structure-activity relationship.

@article{Comalada2006InhibitionOP,
  title={Inhibition of pro-inflammatory markers in primary bone marrow-derived mouse macrophages by naturally occurring flavonoids: analysis of the structure-activity relationship.},
  author={M{\'o}nica Comalada and Isabel Ballester and Elvira Bail{\'o}n and Saleta Sierra and Jordi Xaus and Julio G{\'a}lvez and Ferm{\'i}n S{\'a}nchez de Medina and Antonio Zarzuelo},
  journal={Biochemical pharmacology},
  year={2006},
  volume={72 8},
  pages={
          1010-21
        }
}
Flavonoids possess several biological/pharmacological activities including anticancer, antimicrobial, antiviral, anti-inflammatory, immunomodulatory and antioxidant. The aim of this study was to evaluate the effect of flavonoids on macrophage physiology. For this purpose we selected some flavonoids belonging to the most common and abundant groups (flavonols--quercetin and kaempferol; flavones--diosmetin, apigenin, chrysin and luteolin; isoflavones--genistein and daidzein and flavanones… CONTINUE READING
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