Inhibition of platelet aggregation and reduced formation of thromboxane and lipoxygenase products in platelets by oil of cloves.

@article{Srivastava1987InhibitionOP,
  title={Inhibition of platelet aggregation and reduced formation of thromboxane and lipoxygenase products in platelets by oil of cloves.},
  author={K. Srivastava and U. Justesen},
  journal={Prostaglandins, leukotrienes, and medicine},
  year={1987},
  volume={29 1},
  pages={
          11-8
        }
}
  • K. Srivastava, U. Justesen
  • Published 1987
  • Chemistry, Medicine
  • Prostaglandins, leukotrienes, and medicine
  • Oil of cloves (OC) was found to be a potent inhibitor of platelet aggregation induced by arachidonic acid (AA), collagen and epinephrine; in this respect it was most effective against AA-induced aggregation. Inhibition of aggregation by OC seems to be mediated through a reduced formation of thromboxane as indicated by the following experimental evidence. (i) OC inhibited TxB2 formation in intact as well as lysed platelet preparations from added arachidonate, and (ii) it inhibited the formation… CONTINUE READING
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