Inhibition of platelet adhesion and thrombus formation on a collagen-coated surface by novel carbamoylpiperidine antiplatelet agents.

@article{Alevriadou1992InhibitionOP,
  title={Inhibition of platelet adhesion and thrombus formation on a collagen-coated surface by novel carbamoylpiperidine antiplatelet agents.},
  author={B. R. Alevriadou and L. Mcintire and A. Lasslo},
  journal={Biochimica et biophysica acta},
  year={1992},
  volume={1137 3},
  pages={
          279-86
        }
}
  • B. R. Alevriadou, L. Mcintire, A. Lasslo
  • Published 1992
  • Chemistry, Medicine
  • Biochimica et biophysica acta
  • The inhibitory effect of two novel antiplatelet agents, 1,10-bis[3-(N,N-diethylcarbamoyl)piperidino]decane dihydrobromide (G-110) and 1,6-bis[3-(N,N-diethylcarbamoyl)piperidino]hexane dihydrobromide (G-112), on platelet adhesion and subsequent aggregation on collagen-coated surface was evaluated under controlled flow. Glass coverslips coated with bovine fibrillar collagen type I were exposed to heparinized human whole blood that had been preincubated with either aqueous solutions of one of the… CONTINUE READING
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