Inhibition of platelet activation by 5-aminosalicylic acid in inflammatory bowel disease.

@article{Carty2000InhibitionOP,
  title={Inhibition of platelet activation by 5-aminosalicylic acid in inflammatory bowel disease.},
  author={Edward Carty and Matthew Ryan Macey and David S Rampton},
  journal={Alimentary pharmacology & therapeutics},
  year={2000},
  volume={14 9},
  pages={1169-79}
}
BACKGROUND Platelets play an important role in inflammation and are activated in inflammatory bowel disease. Micro-vascular thrombosis in the gut wall leading to intestinal micro-infarction may be a pathogenic feature of Crohn's disease. 5-Aminosalicylic acid is an effective treatment for patients with inflammatory bowel disease. AIMS To assess the effects of 5-aminosalicylic acid on platelet activation, when taken orally and in vitro by patients with inflammatory bowel disease. METHODS… CONTINUE READING
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