Inhibition of phagosome-lysosome fusion in ovine polymorphonuclear leucocytes by Ehrlichia (Cytoecetes) phagocytophila.

@article{Gokce1999InhibitionOP,
  title={Inhibition of phagosome-lysosome fusion in ovine polymorphonuclear leucocytes by Ehrlichia (Cytoecetes) phagocytophila.},
  author={Halil Ibrahim Gokce and Genevi{\`e}ve Ross and Zerai Woldehiwet},
  journal={Journal of comparative pathology},
  year={1999},
  volume={120 4},
  pages={369-81}
}
Ehrlichia (Cytoecetes) phagocytophila, the causative agent of tick-borne fever, is an intracellular bacterium that survives and multiplies within granulocytes and monocytes. In the present study, the possible fusion of lysosomes with phagosomes containing E. phagocytophila was investigated in poly-morphonuclear (PMN) cells of sheep infected with the agent, acid phosphatase cytochemistry and cationized ferritin being used as markers of primary and secondary lysosomal enzymes. Latex beads or… CONTINUE READING