Inhibition of parathormone-stimulated bone resorption by type I interferon.

@article{Jilka1984InhibitionOP,
  title={Inhibition of parathormone-stimulated bone resorption by type I interferon.},
  author={Robert L. Jilka and Joshua W. Hamilton},
  journal={Biochemical and biophysical research communications},
  year={1984},
  volume={120 2},
  pages={553-8}
}
The effect of Type I interferon on bone resorption was studied by measuring its effect on parathormone-stimulated calcium release from neonatal murine calvaria in vitro. A pure human recombinant leukocyte interferon hybrid of the A and D subtypes was used, which has high antiviral activity on mouse cells. Calcium release was inhibited in a dose dependent fashion with 50% inhibition at about 10(-10) M or 600 U/ml, and the inhibition was reversible. The presence of interferon was required before… CONTINUE READING
2 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-2 of 2 extracted citations

Similar Papers

Loading similar papers…