Inhibition of oxidative phosphorylation for enhancing citric acid production by Aspergillus niger

@inproceedings{Wang2015InhibitionOO,
  title={Inhibition of oxidative phosphorylation for enhancing citric acid production by Aspergillus niger},
  author={Lu Wang and Jianhua Zhang and Zhanglei Cao and Yajun Wang and Qiang Gao and Jian Zhang and Depei Wang},
  booktitle={Microbial cell factories},
  year={2015}
}
BACKGROUND The spore germination rate and growth characteristics were compared between the citric acid high-yield strain Aspergillus niger CGMCC 5751 and A. niger ATCC 1015 in media containing antimycin A or DNP. We inferred that differences in citric acid yield might be due to differences in energy metabolism between these strains. To explore the impact of energy metabolism on citric acid production, the changes in intracellular ATP, NADH and NADH/NAD+ were measured at various fermentation… CONTINUE READING