Inhibition of ovulation by a triphasic gestodene-containing oral contraceptive.

  title={Inhibition of ovulation by a triphasic gestodene-containing oral contraceptive.},
  author={J{\"u}rgen Spona and U Lachnit-Fixson and Bernd D{\"u}sterberg and Karl Dobianer},
  journal={Advances in contraception : the official journal of the Society for the Advancement of Contraception},
  volume={9 3},
The minimal effective dose of gestodene for inhibition of ovulation was studied in 30 female volunteers. Daily doses of 10 micrograms to 50 micrograms gestodene were given orally for 21 days. A control cycle prior to treatment and a treatment cycle were monitored for LH, FSH, estradiol, progesterone and cervical score. At a daily dose of 40 micrograms of gestodene, 6/7 volunteers exhibited inhibition of ovulation and 1/7 had a cycle with luteal insufficiency. Ovulation was inhibited in all… CONTINUE READING
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