Inhibition of osteopontin suppresses in vitro and in vivo angiogenesis in endometrial cancer.

Abstract

OBJECTIVE Osteopontin (OPN) has been found to play an important role in tumor angiogenesis in recent years. Our previous studies have shown that OPN is overexpressed in tumor-associated human endometrial endothelial cells (HEECs) isolated from tissue samples of patients with endometrial cancer. In the present study, we aimed to further determine the role of… (More)
DOI: 10.1016/j.ygyno.2009.08.029

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