Inhibition of osteoclast-like cell formation by sodium salicylate and indomethacin in mouse bone marrow culture.

  • A. Soekanto
  • Published 1994 in Japanese journal of pharmacology


The present study examined the effect of sodium salicylate and indomethacin on the recruitment of osteoclast-like cells in vitro. When mouse bone marrow cells were cultured for 8 days with 1 alpha,25-dihydroxyvitamin D3 (1 alpha,25-(OH)2D3, 10(-8) M), prostaglandin E2 (PGE2, 10(-6) M) and recombinant human interleukin-1 alpha (rHIL-1 alpha, 2 ng/ml… (More)


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