Inhibition of oncogene expression by green tea and (-)-epigallocatechin gallate in mice.

@article{Hu1995InhibitionOO,
  title={Inhibition of oncogene expression by green tea and (-)-epigallocatechin gallate in mice.},
  author={G. G. Hu and Chi Soo Han and Junshi Chen},
  journal={Nutrition and cancer},
  year={1995},
  volume={24 2},
  pages={203-9}
}
The effects of tea drinking on the tobacco-specific nitrosamine 4-(methylnitrosamine)-1-(3-pyridyl)-1-butanone (NNK)-induced mouse lung oncogene expression and the effect of topical application of the tea polyphenol component (-)-epigallocatechin-3-gallate (EGCG) on 12-O-tedradecanoylphorbol-13-acetate (TPA)-induced mouse skin oncogene expression were investigated. In the first experiment, mice were treated with NNK (1.3 mg/kg body wt ip) once a day for three days and were given 2% tea in… CONTINUE READING

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