Inhibition of nitric oxide production in lipopolysaccharide-activated RAW 264.7 macrophages by Jeju plant extracts

@inproceedings{Yang2009InhibitionON,
  title={Inhibition of nitric oxide production in lipopolysaccharide-activated RAW 264.7 macrophages by Jeju plant extracts},
  author={Eun-Jin Yang and Eun-Young Yim and Gwanpil Song and G H Kim and Chang-Gu Hyun},
  booktitle={Interdisciplinary toxicology},
  year={2009}
}
Nitric oxide (NO) produced in large amounts by inducible nitric oxide synthase (iNOS) is known to be responsible for the vasodilation and hypotension observed during septic shock and inflammation. Thus, inhibitors of iNOS may be useful candidates for the treatment of inflammatory diseases accompanied by the overproduction of NO. In this study, we prepared alcoholic extracts of Jeju plants and screened them for their inhibitory activity against NO production in lipopolysaccharide (LPS)-activated… CONTINUE READING
Highly Cited
This paper has 240 citations. REVIEW CITATIONS

1 Figure or Table

Topics

Statistics

050100201020112012201320142015201620172018
Citations per Year

241 Citations

Semantic Scholar estimates that this publication has 241 citations based on the available data.

See our FAQ for additional information.