Inhibition of neuronal cell death after retinoic acid-induced down-regulation of P2X7 nucleotide receptor expression

@article{Orellano2009InhibitionON,
  title={Inhibition of neuronal cell death after retinoic acid-induced down-regulation of P2X7 nucleotide receptor expression},
  author={Elsie A. Orellano and Omayra J. Rivera and Migdalia Chevres and Nataliya E. Chorna and F. A. Castillo Gonz{\'a}lez},
  journal={Molecular and Cellular Biochemistry},
  year={2009},
  volume={337},
  pages={83-99}
}
Apoptosis is a major mechanism for cell death in the nervous system during development. P2X7 nucleotide receptors are ionotropic ATP receptors that mediate cell death under pathological conditions. We developed an in vitro protocol to investigate the expression and functional responses of P2X7 nucleotide receptors during retinoic acid (RA)-induced neuronal differentiation of human SH-SY5Y neuroblastoma cells. Neuronal differentiation was examined measuring cellular growth arrest and neuritic… CONTINUE READING
12 Citations
70 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 12 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 70 references

Similar Papers

Loading similar papers…