Inhibition of monocyte-derived inflammatory cytokines by IL-25 occurs via p38 Map kinase-dependent induction of Socs-3.

@article{Caruso2009InhibitionOM,
  title={Inhibition of monocyte-derived inflammatory cytokines by IL-25 occurs via p38 Map kinase-dependent induction of Socs-3.},
  author={R. Caruso and C. Stolfi and M. Sarra and A. Rizzo and M. Fantini and F. Pallone and T. Macdonald and G. Monteleone},
  journal={Blood},
  year={2009},
  volume={113 15},
  pages={
          3512-9
        }
}
  • R. Caruso, C. Stolfi, +5 authors G. Monteleone
  • Published 2009
  • Medicine, Biology
  • Blood
  • IL-25, a member of the IL-17 cytokine family, is known to enhance Th2-like responses associated with increased serum levels of IgE, IgG1, IgA, blood eosinophilia, and eosinophilic infiltrates in various tissues. However, IL-25 also abrogates inflammatory responses driven by Th17 cells. However, the cell types that respond to IL-25 and the mechanisms by which IL-25 differentially regulates immune reactions are not well explored. To identify potential targets of IL-25, we initially examined IL-25… CONTINUE READING
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