Inhibition of microsomal glucose-6-phosphatase induced by ferrylmyoglobin.

Ferrylmyoglobin (ferrylMb) caused inhibition of microsomal glucose-6-phosphatase (G6Pase) during membrane lipid peroxidation. Butylated hydroxytoluene prevented both the inactivation of G6Pase and the lipid peroxidation. Furthermore, ferrylMb was adsorbed on to the membranes and the membrane proteins polymerized during the lipid peroxidation, suggesting… CONTINUE READING