Inhibition of mesenchymal stromal cells by pre-activated lymphocytes and their culture media

Abstract

Despite having a proven immunosuppressive potential in vitro, human mesenchymal stromal cells (MSCs) are reported to display variable efficacy in vivo and, in fact, their proven benefit in the clinical practice is still limited and controversial. The interplay between clinical grade MSCs and pre-activated donor lymphocytes or selected lymphocyte subsets was… (More)
DOI: 10.1186/scrt392

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