Inhibition of mast cell-dependent allergy reaction by extract of black cohosh (Cimicifuga racemosa).

@article{Kim2004InhibitionOM,
  title={Inhibition of mast cell-dependent allergy reaction by extract of black cohosh (Cimicifuga racemosa).},
  author={Chang Deok Kim and Won-Kyung Lee and Min-Ho Lee and Ho Song Cho and Yong Koo Lee and S S Roh},
  journal={Immunopharmacology and immunotoxicology},
  year={2004},
  volume={26 2},
  pages={299-308}
}
Black cohosh (Cimicifuga racemosa) has been used as therapeutics for pain and inflammation in Korean folk medicine. The potential effects of black cohosh extract (BCE) on mast cell-dependent allergy reaction, however, have not been well elucidated yet. In the present study, we investigated the effect of BCE on the allergy reaction using mast cell-dependent in vivo and in vitro models. BCE showed no potential of skin sensitization in local lymph node assay (LLNA). The oral administration of BCE… CONTINUE READING