Inhibition of marine biofouling by bacterial quorum sensing inhibitors

@article{Dobretsov2011InhibitionOM,
  title={Inhibition of marine biofouling by bacterial quorum sensing inhibitors},
  author={Sergey Dobretsov and Max Teplitski and Mirko Bayer and Sarath P. Gunasekera and Peter Proksch and Valerie J. Paul},
  journal={Biofouling},
  year={2011},
  volume={27},
  pages={893 - 905}
}
Seventy eight natural products from chemical libraries containing compounds from marine organisms (sponges, algae, fungi, tunicates and cyanobacteria) and terrestrial plants, were screened for the inhibition of bacterial quorum sensing (QS) using a reporter strain Chromobacterium violaceum CV017. About half of the natural products did not show any QS inhibition. Twenty four percent of the tested compounds inhibited QS of the reporter without causing toxicity. The QS inhibitory activities of the… Expand
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