Corpus ID: 39053105

Inhibition of macrophage-dependent low density lipoprotein oxidation by nitric-oxide donors.

@article{Hogg1995InhibitionOM,
  title={Inhibition of macrophage-dependent low density lipoprotein oxidation by nitric-oxide donors.},
  author={N. Hogg and A. Struck and S. P. Goss and N. Santanam and J. Joseph and S. Parthasarathy and B. Kalyanaraman},
  journal={Journal of lipid research},
  year={1995},
  volume={36 8},
  pages={
          1756-62
        }
}
We have previously shown that nitric oxide donors inhibit the oxidation of low density lipoprotein (LDL) initiated by copper ions or by azo-bis-amidinopropane (Hogg et al., 1993. FEBS Lett. 334: 170-174). In this study, the nitric oxide donors S-nitroso-N-acetylpenicillamine (SNAP), spermine NONOate, and sodium nitroprusside were tested for their ability to inhibit macrophage-dependent oxidation of LDL. SNAP and spermine NONOate inhibited macrophage-dependent oxidation of LDL in a time- and… Expand
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