Inhibition of macrophage apoptosis by Neisseria meningitidis requires nitric oxide detoxification mechanisms.

@article{Tunbridge2006InhibitionOM,
  title={Inhibition of macrophage apoptosis by Neisseria meningitidis requires nitric oxide detoxification mechanisms.},
  author={Anne J Tunbridge and T{\^a}nia M. Stevanin and Margaret T. Lee and Helen M. Marriott and James W. B. Moir and Robert C Read and David H Dockrell},
  journal={Infection and immunity},
  year={2006},
  volume={74 1},
  pages={729-33}
}
Host-driven macrophage apoptosis contributes to innate immunity during bacterial infection. Neisseria meningitidis inhibits apoptosis in a variety of cells, but its impact on macrophage apoptosis is unknown. We demonstrate that N. meningitidis prevents macrophage apoptosis via genes encoding nitric oxide detoxification and a porin, PorB.