Inhibition of liver alanine aminotransferase and aspartate aminotransferase by hesperidin and its aglycone hesperetin: An in vitro and in silico study

@article{Zareei2017InhibitionOL,
  title={Inhibition of liver alanine aminotransferase and aspartate aminotransferase by hesperidin and its aglycone hesperetin: An in vitro and in silico study},
  author={S. Zareei and M. Boojar and M. Amanlou},
  journal={Life Sciences},
  year={2017},
  volume={178},
  pages={49–55}
}
Aims: This study aimed to investigate the inhibitory effects of two natural flavonoids, hesperetin (HT) and hesperidin (HD), on two gluconeogenesis enzymes, alanine aminotransferase (ALT) and aspartate aminotransferase (AST) activities and their possible mechanisms of action. Main methods: Rat liver incubated with different concentrations of HT and HD was used to measure enzyme activities spectrophotometrically, based on monitoring the oxidation of NADH to NAD+ at 340 nm. Molecular docking… Expand
Hesperidin: A Therapeutic Agent For Obesity
DDDT_A_227499 3855..3866
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References

SHOWING 1-10 OF 43 REFERENCES
Protective effects of Parinari curatellifolia flavonoids against acetaminophen-induced hepatic necrosis in rats.
Specific inhibition of the aspartate aminotransferase of Plasmodium falciparum.
The flavonoid naringenin inhibits dimethylnitrosamine-induced liver damage in rats.
...
1
2
3
4
5
...