Inhibition of lipoxygenase-dependent lipid peroxidation by quercetin: Mechanism of antioxidative function

@inproceedings{Takahama1985InhibitionOL,
  title={Inhibition of lipoxygenase-dependent lipid peroxidation by quercetin: Mechanism of antioxidative function},
  author={Umeo Takahama},
  year={1985}
}
  • Umeo Takahama
  • Published 1985
  • Biology
  • Abstract Quercetin inhibited soybean lipoxygenase-1-dependent linoleic acid peroxidation. Two to three μM quercetin was required for 50% inhibition. During the inhibition, quercetin was oxidized. The oxidation was observed as an absorbance decrease at about 380 nm and an absorbance increase at about 335 nm. Inhibition of linoleic acid peroxidation by quercetin seems to be due to reduction by the reagent of the linoleic acid radical formed as an intermediate during lipoxygenation. Quercetin… CONTINUE READING

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