Inhibition of lecithin:cholesterol acyltransferase in human plasma by dicarboxylic lecithins.

@article{Dousset1978InhibitionOL,
  title={Inhibition of lecithin:cholesterol acyltransferase in human plasma by dicarboxylic lecithins.},
  author={N. Dousset and J. Dousset and G. Soula and L. Douste-Blazy},
  journal={Scandinavian journal of clinical and laboratory investigation. Supplementum},
  year={1978},
  volume={150},
  pages={
          21-5
        }
}
  • N. Dousset, J. Dousset, +1 author L. Douste-Blazy
  • Published 1978
  • Chemistry, Medicine
  • Scandinavian journal of clinical and laboratory investigation. Supplementum
  • The effect of dicarboxylic lecithins on the lecithin:cholesterol acyltransferase [LCAT] activity was studied with a partially purified preparation [approximately 24-fold]. The presence of dicarboxylic lecithins is followed by the inhibition of LCAT. The inhibition is proportional to the concentration of glutaryl-lecithin and is about 50% with 0.16 mM glutaryl-lecithin. For a higher concentration, the inhibition is total. The inhibition of LCAT activity was of a mixed type. It can be explained… CONTINUE READING
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