Inhibition of intravascular platelet aggregation by endothelium-derived relaxing factor: reversal by red blood cells.

@article{Houston1990InhibitionOI,
  title={Inhibition of intravascular platelet aggregation by endothelium-derived relaxing factor: reversal by red blood cells.},
  author={Donald Stuart Houston and Peter Robinson and Jonathan M. Gerrard},
  journal={Blood},
  year={1990},
  volume={76 5},
  pages={953-8}
}
Studies were performed to determine whether endothelium-derived relaxing factor (EDRF) can inhibit platelet aggregation within the vascular lumen, and if so, whether the inhibition persists in the presence of red blood cells (RBCs). Canine femoral arteries mounted in an organ bath were perfused with physiologic saline solution to which acetylsalicylic acid was added to block prostacyclin formation. During contraction with phenylephrine, addition of acetylcholine to the perfusing solution to… CONTINUE READING
6 Citations
33 References
Similar Papers

References

Publications referenced by this paper.
Showing 1-10 of 33 references

Similar Papers

Loading similar papers…