Inhibition of interleukin-1 beta-induced pyresis in the rabbit by peptide 204-212 of lipocortin 5.

@article{Palmi1995InhibitionOI,
  title={Inhibition of interleukin-1 beta-induced pyresis in the rabbit by peptide 204-212 of lipocortin 5.},
  author={Mitri Palmi and Maria Frosini and Gian Pietro Sgaragli and C. Becherucci and Mauro Perretti and Luca Parente},
  journal={European journal of pharmacology},
  year={1995},
  volume={281 1},
  pages={97-9}
}
The intracerebroventricular administration of interleukin-1 beta (12.5 ng/kg) in rabbits caused a prompt rise of prostaglandin E2 concentration (+ 632.6 +/- 243.9%) in the cerebrospinal fluid followed by hyperthermia (+ 1.61 +/- 0.14 delta degrees C). The intracerebroventricular administration of an anti-inflammatory nonapeptide (amino acids 204-212… CONTINUE READING