Inhibition of infection-mediated preterm birth by administration of broad spectrum chemokine inhibitor in mice

@inproceedings{Shynlova2014InhibitionOI,
  title={Inhibition of infection-mediated preterm birth by administration of broad spectrum chemokine inhibitor in mice},
  author={Oksana Shynlova and Anna Dorogin and Yunqing Li and Stephen James Lye},
  booktitle={Journal of cellular and molecular medicine},
  year={2014}
}
Preterm birth (PTB) is the single most important cause of perinatal and infant mortality worldwide. Maternal infection can result in PTB. We investigated the ability of a Broad Spectrum Chemokine Inhibitor (BSCI) to prevent infection-induced PTB in mice. PTB was initiated in pregnant mice by intraperitoneal injection of lipopolysaccharide (LPS; 50 μg). Half the mice received BSCI (10 mg/kg) 24 hrs prior to and immediately before LPS administration. The impact of LPS alone or LPS plus BSCI was… CONTINUE READING
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Born too soon: global action report on preterm birth

  • CP Howson
  • Geneva: WHO,
  • 2012
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