Inhibition of in vivo proliferation of androgen-independent prostate cancers by an antagonist of growth hormone-releasing hormone.

@article{Jungwirth1997InhibitionOI,
  title={Inhibition of in vivo proliferation of androgen-independent prostate cancers by an antagonist of growth hormone-releasing hormone.},
  author={A. Jungwirth and A. Schally and J. Piński and G. Halmos and K. Groot and P. Armatis and M. Vadillo-Buenfil},
  journal={British Journal of Cancer},
  year={1997},
  volume={75},
  pages={1585 - 1592}
}
  • A. Jungwirth, A. Schally, +4 authors M. Vadillo-Buenfil
  • Published 1997
  • Medicine
  • British Journal of Cancer
  • Tumour-inhibitory effects of a new antagonist of growth hormone-releasing hormone (GH-RH), MZ-4-71, were evaluated in nude mice bearing androgen-independent human prostate cancer cell lines DU-145 and PC-3 and in Copenhagen rats implanted with Dunning R-3327 AT-1 prostatic adenocarcinoma. After 6 weeks of therapy, the tumour volume in nude mice with DU-145 prostate cancers treated with 40 microg day(-1) MZ-4-71 was significantly decreased to 37 +/- 13 mm3 (P < 0.01) compared with controls that… CONTINUE READING
    77 Citations
    Growth hormone-releasing hormone (GHRH) antagonists inhibit the proliferation of androgen-dependent and -independent prostate cancers
    • 69
    • PDF
    Inhibition of growth of experimental human endometrial cancer by an antagonist of growth hormone-releasing hormone.
    • 31
    • PDF
    Antagonists of growth hormone-releasing hormone arrest the growth of MDA-MB-468 estrogen-independent human breast cancers in nude mice
    • 55
    Antagonists of growth hormone-releasing hormone inhibit the proliferation of experimental non-small cell lung carcinoma.
    • 47
    • PDF
    Decrease in telomerase activity in U-87MG human glioblastomas after treatment with an antagonist of growth hormone-releasing hormone.
    • H. Kiaris, A. Schally
    • Medicine, Biology
    • Proceedings of the National Academy of Sciences of the United States of America
    • 1999
    • 61
    • PDF

    References

    SHOWING 1-10 OF 46 REFERENCES
    Inhibition of growth of human osteosarcomas by antagonists of growth hormone-releasing hormone.
    • 86