Inhibition of in vivo angiogenesis by N-beta-alanyl-5-S-glutathionyl-3,4-dihydroxyphenylalanine.


N-beta-alanyl-5-S-glutathionyl-3,4-dihydroxyphenylalanine (5-S-GAD), an antibacterial substance isolated from the flesh fly, inhibits human tumor growth in the nude mice model; however, the mechanism of its action is unclear. The in vivo antitumor effect includes the inhibition of tumor cell proliferation and suppression of angiogenesis. Angiogenesis is… (More)


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@article{Nishikawa2006InhibitionOI, title={Inhibition of in vivo angiogenesis by N-beta-alanyl-5-S-glutathionyl-3,4-dihydroxyphenylalanine.}, author={Takeshi Nishikawa and Nobuko Akiyama and Kazuhiro Kunimasa and Tsutomu Oikawa and Masaaki Ishizuka and M. Tsujimoto and Shunji Natori}, journal={European journal of pharmacology}, year={2006}, volume={539 3}, pages={151-7} }