Inhibition of human neutrophil bacteriocidal activity by extracellular substance from slime-producing Staphylococcus epidermidis.

@article{Noble1986InhibitionOH,
  title={Inhibition of human neutrophil bacteriocidal activity by extracellular substance from slime-producing Staphylococcus epidermidis.},
  author={Michael A. Noble and Philip E. Reid and C M Park and Vivian Chan},
  journal={Diagnostic microbiology and infectious disease},
  year={1986},
  volume={4 4},
  pages={
          335-9
        }
}
The role of slime produced by Staphylococcus epidermidis as a virulence factor has been investigated by preincubating human neutrophils in fractions of extracellular material from cultures of slime-producing and non-slime-producing S. epidermidis. Extracellular product (molecular weight greater than 300,000) from slime-producing S. epidermidis did not affect neutrophil phagocytosis but did produce a generalized loss of bacteriocidal activity which was not found with non-slime-producing S… CONTINUE READING