[Inhibition of human macrophage-derived foam cell differentiation by blocking Kv1.3 and Kir2.1 channels].

Abstract

OBJECTIVE To investigate the expression of Kv1.3 and Kir2.1 during human monocyte-derived macrophages differentiation into foam cells and their function in foam cells formation. METHODS The human macrophage-derived foam cells were obtained by incubating macrophages with ox-LDL (30 mg/L) for 60 h. The expression of Kv1.3 and Kir2.1 channels were examined… (More)

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@article{Lei2006InhibitionOH, title={[Inhibition of human macrophage-derived foam cell differentiation by blocking Kv1.3 and Kir2.1 channels].}, author={Xin-jun Lei and Ai-qun Ma and Yu-tao Xi and Wei Zhang and Yan Yao and Yuan Y Du}, journal={Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences}, year={2006}, volume={31 4}, pages={493-8} }