Inhibition of human immunodeficiency virus type 1 (HIV-1) replication by a two-amino-acid insertion in HIV-1 Vif from a nonprogressing mother and child.

@article{Alexander2002InhibitionOH,
  title={Inhibition of human immunodeficiency virus type 1 (HIV-1) replication by a two-amino-acid insertion in HIV-1 Vif from a nonprogressing mother and child.},
  author={Louis Alexander and Mary Janette Aquino-DeJesus and Michael Kam-tim Chan and Warren A. Andiman},
  journal={Journal of virology},
  year={2002},
  volume={76 20},
  pages={10533-9}
}
We studied a 15-year-old girl, patient X, who has maintained consistently low plasma loads of human immunodeficiency virus type 1 (HIV-1) RNA, as well as normal and stable CD4(+) T-cell concentrations. She has presented no clinical manifestations of AIDS, despite having only received zidovudine monotherapy for a part of her life. Patient X's HIV-positive… CONTINUE READING