Inhibition of human immunodeficiency virus expression by sense transcripts encoding the retroviral leader RNA.


Towards gene therapy for the treatment of human immunodeficiency virus type 1 (HIV-1) infections, we tested the potency of several antiviral constructs in transient HIV-1 production assays. Whereas little effect was obtained with antisense- and TAR decoy-constructs, we measured efficient inhibition of HIV-1 mRNA translation and virion production in the… (More)


Figures and Tables

Sorry, we couldn't extract any figures or tables for this paper.