Inhibition of human immunodeficiency virus (HIV-1) infection by diphenylhydantoin (dilantin) implicates role of cellular calcium in virus life cycle.

Abstract

Details of the molecular interactions between human immunodeficiency virus (HIV-1) and its host cell during the infection process are not entirely clear. Building on recent reports by Lehr and Zimmer (1986, DMW 111, 1001-1002) that the membrane-reactive, anti-epileptic drug diphenylhydantoin (dilantin or phenytoin) (PHT) inhibited binding of HIV to… (More)

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Cite this paper

@article{Cloyd1989InhibitionOH, title={Inhibition of human immunodeficiency virus (HIV-1) infection by diphenylhydantoin (dilantin) implicates role of cellular calcium in virus life cycle.}, author={Miles W. Cloyd and William S. Lynn and Kathryn Moynihan Ramsey and Samuel Baron}, journal={Virology}, year={1989}, volume={173 2}, pages={581-90} }