Inhibition of high-density growth arrest in human squamous carcinoma cells by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD).

Abstract

The highly toxic environmental contaminant 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is a potent carcinogen and tumor promoter, and affects cellular proliferation and differentiation both in vivo and in vitro. This report presents data showing that TCDD enhances the proliferation of two human squamous carcinoma cell lines in monolayer culture by inhibiting… (More)

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