Inhibition of herpes virus-induced cell fusion by concanavalin A, antisera, and 2-deoxy-D-glucose.

@article{Ludwig1974InhibitionOH,
  title={Inhibition of herpes virus-induced cell fusion by concanavalin A, antisera, and 2-deoxy-D-glucose.},
  author={Holger Ludwig and H. Becht and Rudolf Rott},
  journal={Journal of virology},
  year={1974},
  volume={14 2},
  pages={307-14}
}
Pseudorabies virus-induced cell fusion in rabbit kidney cells can be prevented by Concanavalin A added early after infection. The infected cells are not agglutinated and the infectivity of cell-free virus is not reduced. Sera from productively infected animals also inhibit polykaryocytosis, whereas a hyperimmune serum directed against virus structural components has no effect. 2-Deoxy-d-glucose reversibly disturbs virus-induced fusion and reduces significantly the virus infectivity. 

Citations

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XC cell fusion by murine leukemia viruses: Fusion from without

Medical Microbiology and Immunology • 1976
View 1 Excerpt

Current Topics in Microbiology and Immunology

Martinsried f. H. Humphrey, Peter K. Vogt
Current Topics in Microbiology and Immunology • 1975

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