Inhibition of hepatitis C virus replication by semi-synthetic derivatives of glycopeptide antibiotics.

Abstract

OBJECTIVES Some semi-synthetic derivatives of glycopeptide antibiotics have been shown to exert in vitro antiviral activity against HIV and coronaviruses. Here we report and characterize the in vitro anti-hepatitis C virus (HCV) activity of several semi-synthetic derivatives of teicoplanin aglycone. METHODS Anti-HCV activity was analysed in: (i) three… (More)
DOI: 10.1093/jac/dkr104

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