Inhibition of hepatic lipase activity impairs chylomicron remnant-removal in rats.

Abstract

[4-14C]Cholesteryl oleyl ether-labeled chylomicron remnants were injected into rats which received a specific goat antibody against rat hepatic lipase or a control serum. Chylomicron remnant cholesterol ether disappeared from circulation with a significantly higher half-life (2-fold) in antibody-treated rats than in controls (P less than 0.001). Recovered… (More)

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@article{Sultan1990InhibitionOH, title={Inhibition of hepatic lipase activity impairs chylomicron remnant-removal in rats.}, author={F. Sultan and Denis Lagrange and H. Jansen and Sabine Griglio}, journal={Biochimica et biophysica acta}, year={1990}, volume={1042 1}, pages={150-2} }