Inhibition of hBD-3, but not hBD-1 and hBD-2, mRNA expression by corticosteroids.

@article{Duits2001InhibitionOH,
  title={Inhibition of hBD-3, but not hBD-1 and hBD-2, mRNA expression by corticosteroids.},
  author={Louise A Duits and Mirjam T G A Rademaker and Bep Ravensbergen and Marian A J A van Sterkenburg and Elisabeth van Strijen and Pieter S Hiemstra and Peter H Nibbering},
  journal={Biochemical and biophysical research communications},
  year={2001},
  volume={280 2},
  pages={522-5}
}
Intensive use of corticosteroids may be accompanied by increased susceptibility to infections; hence, we investigated the effects of dexamethasone on the expression of antimicrobial peptides, termed human beta-defensins (hBD), by cultured bronchial epithelial cells and mononuclear phagocytes. The results revealed that dexamethasone inhibited the (stimulated… CONTINUE READING