Inhibition of growth of OV-1063 human epithelial ovarian cancers and c- jun and c- fos oncogene expression by bombesin antagonists

Abstract

Receptors for bombesin are present on human ovarian cancers and bombesin-like peptides could function as growth factors in this carcinoma. Therefore, we investigated the effects of bombesin/gastrin-releasing peptide (GRP) antagonists RC-3940-II and RC-3095 on the growth of human ovarian carcinoma cell line OV-1063, xenografted into nude mice. Treatment with… (More)
DOI: 10.1054/bjoc.2000.1374

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@article{Chatzistamou2000InhibitionOG, title={Inhibition of growth of OV-1063 human epithelial ovarian cancers and c- jun and c- fos oncogene expression by bombesin antagonists}, author={Ioulia Chatzistamou and Andrew V Schally and B. Sun and Patricia Armatis and Karoly Szepesh{\'a}zi}, journal={British Journal of Cancer}, year={2000}, volume={83}, pages={906 - 913} }