Inhibition of growth and metastasis of syngeneic transplantable tumours by an aromatic retinoic acid analogue

Abstract

An aromatic retinoic acid analogue (Ro 10-9359) previously shown to be capable of inhibiting the growth and metastasis of immunogenic sarcomas and carcinomas (see accompanying paper) was tested for its anti-tumour effects in various categories of immune-deprived mice. ‘Non-specific’ immunosuppression evoked by sub-lethal whole-body X-irradiation abolished… (More)
DOI: 10.1007/BF00199718

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