Inhibition of glycosylation prevents H‐2K and D antigen expression on SV40 virus‐transformed cells

@article{Swaminathan1983InhibitionOG,
  title={Inhibition of glycosylation prevents H‐2K and D antigen expression on SV40 virus‐transformed cells},
  author={S. Swaminathan and L. Gooding},
  journal={European Journal of Immunology},
  year={1983},
  volume={13}
}
Tunicamycin, an inhibitor of glycosylation, was used to examine the role of carbohydrate moieties of glycoproteins involved in recognition of Simian virus 40 (SV40)‐transformed cells by cytotoxic T lymphocytes (CTL). Tunicamycin treatment renders such cells refractory to lysis by H‐2 restricted, SV40‐specific CTL as well as by allogeneic CTL directed only against H‐2 antigens. Treated cells are no longer susceptible to lysis by anti‐H‐2 antisera and complement, nor are they stained by… Expand
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Macrophages in Immunoparasitology

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